Martha loses her mind after her child's death; Martha's "Joker smile" was from her son's blood as her sorrow turns into insane laughter. Batman later fights Yo-Yo for the Joker's whereabouts and also compares Eobard Thawne's deranged psychosis to the Joker's insanity.
When her son Bruce was ten, Martha and her husband Thomas were murdered in front of him.
- Justice League: The Flashpoint Paradox
- Justice League: War (mentioned)
- Batman vs. Robin
- Batman: Bad Blood
- Martha Wayne first appeared in Detective Comics #33 created by Bob Kane and Bill Finger.